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Sugar-coated Nanoparticles Find Hidden Tumors

Nanoparticles that could first illuminate and then destroy hidden tumors have been created by scientists at the University of California, San Diego.

If approved for clinical use, the new technique could improve the odds of survival for cancer patients by letting doctors diagnose and treat cancer earlier. It would also, in theory, minimize the toxic side effects associated with traditional chemotherapy.

"The advantage is that if the nanostructure localizes [near the tumor], it gives you an improved ability to see or treat the tumor," said Michael Sailor, a scientist at the University of California, San Diego, who detailed the research in a recent issue of Nature Materials.

The drawback to most techniques for finding and treating cancer is toxicity. The same radioactive cadmium that accumulates inside tumors and shines light that MRI machines can detect also destroys various internal organs. Chemotherapy drugs such as abraxane destroy tumor cells but also kill plenty of healthy cells. more